I noticed on the top of my linux server that one CPU had a much larger number of software interrupts than all the other 7 cores. Digging further, I noticed that this kernel is anchored to a particular irq that turns out to be a virtio device. Infact each core has an affinity towards a particular virtio device
virtio0-config virtio0 control virtio0 event virtio0 application virtio2-config virtio2-input.0 virtio2-output.0 virtio3-config virtio3-input.0 virtio3-output.0 virtio4-config virtio4-input.0 virtio4-output.0
In this list, virtio4-input.0 has, in particular, a very high number of interruptions and I can not find out what is special about this particular device. any track will be very useful. The machine in question is a nutanix VM running on a Linux host.